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Complex Regional Pain Syndrome (CRPS) is a neuropathic disorder characterized by severe chronic pain, swelling, and hypersensitivity to touch. As a debilitating, orphan disease that is difficult to diagnose and treat, there is a strong unmet need for new, helpful treatment options.

Dr. Amol Soin, Founder and CEO of Soin Therapeutics, joins us to discuss his orphan drug status from the FDA for low-dose Naltrexone to treat complex regional pain syndrome. This is a non-addicting and non-sedating drug that could be a new way to treat complex regional pain syndrome. Low-dose naltrexone is currently being studied in clinical trials, as a step to achieve FDA approval.

We traveled to Dayton, Ohio, to meet Donna, a busy wife and mother whose life was put to a stop when she started experiencing symptoms. After being diagnosed with CRPS, Donna wants to help others manage this often complicated, invisible illness so they feel less alone.

Credits: Ian Jones & Wikimedia Commons

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