Behind the Mystery: Glioblastoma (GBM)

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GBM is rare brain tumor that carries a poor prognosis.

Glioblastoma (GBM) is a rare brain tumor that can rapidly grow and spread into nearby brain tissue. It is difficult to treat and has a poor prognosis.

Treatment is a challenging task, due to the location and complexity of the tumor. Glioblastoma is not surgically curable because the tumor has left behind cells deep into the brain that can grow again. That’s why many treatments fail or are ineffective for glioblastoma patients. Also, the brain has a special protective barrier called the blood-brain barrier that protects the brain from poison, and most chemotherapies are considered poisonous.

However, progress has been made for treating GBM including the use of Tumor Treating Fields, as well as investigational therapies such as medications that can potentially cross the blood-brain barrier and next-generation sequencing.

We’ll hear more from Dr. Sigmund Hsu and a patient who was diagnosed with a GBM 15 years ago.