Airing weekdays at 7:30 A.M. on

Airing weekdays at 7:30 A.M. on

Arginase 1 Deficiency is an inherited, metabolic disease that is both debilitating and progressive, leading to significant morbidity and early mortality. When there is a mutation in the ARG1 gene, it results in high levels of arginine, which is the primary cause of spasticity, loss of mobility, developmental delay, and seizures.

Currently, there are no approved treatment options. While symptom presentation begins around the age of 2, the average age of diagnosis is 6, causing a 4-year delay in diagnosis, which can lead to disease progression and worsening of clinical outcomes.

If physicians suspect a patient with Arginase 1 Deficiency, the diagnosis can be established easily and reliably with a widely available amino acid panel focused on arginine and a genetic test for the ARG1 mutation.

We met with renowned expert, geneticist Dr. Stephen Cederbaum, as well as Angela, whose 4-year-old son Isaiah is living with this disease.

Mixing it up in sweet and savory ways: We’re featuring the world-famous, award-winning Angostura® aromatic bitters, orange bitters, and the newly introduced cocoa bitters.

Multiple sclerosis (MS) is an autoimmune condition where the immune system inappropriately attacks the brain and the spinal cord.

What women "auto" know about car insurance, plus living with and managing multiple sclerosis, and mixing it up with Angostura coca bitters.