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Alport syndrome is a rare, genetic, and chronic kidney condition characterized by declining kidney function, which can lead to end-stage kidney disease.

All patients experience kidney-related symptoms, and some experience hearing loss and eye abnormalities. Additionally, it’s a highly progressive disease that is often undiagnosed or misdiagnosed.

Alport syndrome is a disease that involves a mutation in the type 4 collagen that can lead to disease in the kidney, eyes, and ears. In many patients, male or female, that kidney function can be lost over time fairly fast.

That can result in significant loss of kidney function, requiring dialysis or transplantation. Furthermore, treating the complications related to the progressive loss of kidney function is very important and is standard of care.

However, there is a significant unmet need regarding delay in progression to the dreaded need for dialysis and transplantation. Stay tuned to learn more.

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